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REUSABLE CUSTOM OLIGO ARRAYS
 CombiMatrix Corporation’s CustomArray™ is a high quality, completely customisable microarray that provides a cost effective and timely solution for microarray users. Oligonucleotide probes can be defined and designed by the user and supported by the open source CombiMatrix probe design system at no additional cost. In addition, the platform takes advantage of equipment used for scanning microscope slide microarrays that avoids the necessity of purchasing additional equipment. The CustomArray™ is manufactured under stringent conditions, and each and every array is quality controlled. The turn around time is typically less than thirty days. Each array can be reused up to 3 times allowing 4 runs out of a single chip or 16 arrays in total for the 4 x 2k platform making these arrays extremely economical.
CustomArray™ uses a specially modified “CMOS” semiconductor to direct the molecular assembly of a specific sequence of DNA bases in response to a digital command. Each feature on the array (a microelectrode) is digitally addressed to selectively generate acid, by means of an electrochemical reaction which, in-turn, controls the detritylation reaction during phosphoramidite synthesis. A software program is used to control the microelectrodes, and thus, the detritylation pattern applied on the chip during synthesis.
More info: CustomArray 12K or CustomArray 4X2K
CombiMatrix has created the first commercially available microarray stripping kit. The kit allows researchers to strip the target from a recently hybridized CustomArray™ enabling a subsequent re-hybridization. With the Stripping Kit, each CustomArray™ can be stripped and re-hybridized three times, yielding a total of four hybridizations and images per CustomArray™. The ability to re-use CustomArray™ microarrays reduces the cost per CustomArray™ to the researcher while eliminating problems associated with chip-to-chip reproducibility.
More info: Stripping Kit
The ability to customise microarray design, layout, and format is essential for many scientists. Combimatrix’s Design-on-Demand™ service supports this process. The investigator is in charge of the experimental design and implements the overall experimental strategy with the assistance of the technical experts at CombiMatrix. Customers can control the entire experimental strategy from start to finish: the investigation, the protocol, the input sequences, and data analysis.
Combimatrix’s Design-on-Demand™ service offers a full line of design services, encompassing the most cutting edge microarray research available in the field today. The Probe Design Suite, which is its backbone, employs an advanced thermodynamic algorithm for cross-hybridisation detections that produces high quality probes for all experimental purposes. The Probe Design Suite also has many other tools that assist in the design process. These tools can be directed to fit your specific need.
More info: Design on Demand
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