A proprietary technology guarantees a reproductible manufacturing process of calibrated magnetic emulsions. The fragmentation under controlled shearing allows for the preparation of 100 to 500 nm uniform magnetic emulsions (see figure below).
The nanoparticles are superparamagnetic : they exhibit magnetic properties only when placed within a magnetic field and show no residual magnetism when removed from this field.
Self-organisation of magnetic particles occurs when stimulated by a magnetic field. Separation is gentle and no column or centrifugations are necessary.
Ademtech has developed in-house polymerisation process ensuring an efficient isolation of the magnetic core, a tuneable functionalisation and a high colloidal stability.
The polymer provides the magnetic core with a uniform protective shell in order to isolate iron oxides that can interfere with some enzymatic reactions (as shown on Transmission Electron Microscopy photos).
The hydrophilic surface lowers non-specific interactions with proteins.
The high magnetic content (more than 70%) ensures a quick and gentle magnetic separation even for the smallest particles with a simple magnet.
Ademtech has developed simple and reproductible protocols for coupling proteins to its nanoparticles yielding to high binding capacities while keeping non-specific binding low and ensuring long-term stability.